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Hugo Lloris and Tottenham suffered Champions League defeat to Monaco on Wednesday

The Champions League has a negative impact on English clubs in their subsequent Premier League fixtures, a Sky Sports study has found.

While Arsenal, Leicester, Manchester City and Tottenham are all odds-on favourites to win their domestic match-ups this weekend, recent history shows teams competing in Europe's elite club competition often suffer a knock-on effect from their midweek exertions.

Arsenal, Manchester City and Chelsea have taken part in the last five Champions League competitions and over that period average a worse points-per-game return in Premier League fixtures taking place after Champions League rounds.

City have suffered more than most, with their points-per-game haul in the Premier League dropping from 2.18 when they haven't played in the Champions League earlier in the week to 1.76 when they have. That's a 19 per cent decrease.

Manchester City's Sergio Aguero scored a hat-trick against Borussia Monchengladbach

Interestingly, City's neighbours Manchester United have proved to be the exception to the rule. Over the past five years, in which United have participated four times in the Champions League, the Old Trafford side actually have a better record in Premier League matches played after those European games.

United have taken an average of 2.09 points per game in the Premier League following Champions League action but that figure drops to 2.01 points per game when they haven't.

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